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Dr. Amjad Awan, MD

Celiac Disease: Signs, Testing and Living Gluten-Free

Sliced bread containing gluten, a trigger for celiac disease

Quick Answer

Celiac disease is an autoimmune condition in which eating gluten, a protein in wheat, barley and rye, triggers the immune system to damage the lining of the small intestine. It affects about 1 in 100 people, and many do not know they have it. Diagnosis usually starts with a blood test and is confirmed with an upper endoscopy and biopsy. Keep eating gluten until testing is complete.

Celiac Disease at a Glance

~1 in 100People affected worldwide
3Grains to avoid: wheat, barley, rye
Blood + biopsyHow diagnosis is confirmed
LifelongGluten-free diet is the treatment

What Happens in Celiac Disease?

The small intestine is lined with tiny, finger-like projections called villi that absorb nutrients. In celiac disease, gluten triggers an immune reaction that flattens these villi, making it harder for your body to absorb vitamins, minerals and calories.

From Gluten to Intestinal Damage

Gluten is eaten

Found in foods made with wheat, barley or rye.

Immune system reacts

In people with celiac disease, the body treats gluten as a threat.

Villi are damaged

Inflammation flattens the lining of the small intestine.

Nutrients are not absorbed

This can lead to anemia, bone loss, fatigue and other problems.

Healing begins

On a strict gluten-free diet, the intestine can heal over months.

Common Signs and Symptoms

Celiac disease looks different in every person. Some have digestive symptoms, others have none at all.

Digestive SymptomsOther Symptoms and Signs
Diarrhea or loose stoolsIron-deficiency anemia
Bloating and gasFatigue and brain fog
Abdominal painItchy, blistering skin rash (dermatitis herpetiformis)
ConstipationBone thinning (osteopenia or osteoporosis)
NauseaMouth ulcers, headaches, joint pain
Unintended weight lossDelayed growth in children; fertility problems

Who Should Be Tested?

Consider Testing If You Have

1
Ongoing GI symptomsChronic diarrhea, bloating or pain.
2
Unexplained anemiaLow iron that does not improve.
3
A close relative with celiacParent, sibling or child.
4
Type 1 diabetesOr autoimmune thyroid disease.
5
Down or Turner syndromeHigher risk conditions.
6
Early bone lossOsteoporosis at a young age.

How Celiac Disease Is Diagnosed

Testing Step by Step

Important: keep eating gluten until all testing is complete

Blood test

A tissue transglutaminase IgA (tTG-IgA) test, often with a total IgA level.

Specialist visit

If the blood test is positive or suspicion is high, a gastroenterologist reviews your results.

Upper endoscopy with biopsy

Small samples from the duodenum confirm the diagnosis.

Treatment plan

Start a strict gluten-free diet and check vitamin, iron and bone health.

Follow-up

Repeat blood tests confirm the diet is working.

Starting a gluten-free diet before testing can cause false-negative results, so talk with your doctor first.

Gluten-Free Food Guide

Usually SafeAvoidCheck the Label
Fresh fruits and vegetablesWheat, including spelt, durum and semolinaOats (choose certified gluten-free)
Meat, poultry, fish and eggsBarley and maltSauces, gravies and soy sauce
Rice, quinoa, corn, potatoesRyeSoups, seasonings and processed meats
Milk, cheese and plain yogurtRegular bread, pasta, crackers and cerealCandy, snacks and salad dressings
Beans, nuts and seedsMost beerMedications and supplements

Look for a certified gluten-free label. A dietitian experienced in celiac disease can help you plan meals.

Avoiding Cross-Contact at Home

  • Use a separate toaster or toaster bags.
  • Keep separate spreads such as butter and peanut butter to avoid crumbs.
  • Clean surfaces and utensils before preparing gluten-free food.
  • Ask questions when eating out about shared fryers and preparation.

Celiac Disease Care in Denton

Dr. Amjad Awan diagnoses and manages celiac disease for patients across Denton County. Call (940) 243-0912, request an appointment, or learn about upper endoscopy in Denton.

Frequently Asked Questions

Is celiac disease the same as gluten intolerance?

No. Celiac disease is an autoimmune condition that damages the intestine. Non-celiac gluten sensitivity can cause symptoms but does not cause the same intestinal damage.

Can celiac disease develop in adults?

Yes. Celiac disease can be diagnosed at any age, including in older adults.

How long does it take to heal?

Many people feel better within weeks, but full healing of the intestine can take months to a few years.

Can I eat a little gluten occasionally?

No. Even small amounts of gluten can cause intestinal damage in people with celiac disease, even without symptoms.

Is celiac disease hereditary?

It runs in families. First-degree relatives of someone with celiac disease have a higher risk and may benefit from testing.

Disclaimer: This article is for general education and does not replace professional diagnosis or treatment. If you have symptoms or questions about your digestive health, please talk with a qualified healthcare provider.

About Dr. Awan
GI doctor in Denton, TX

Dr. Awan has cared for patients in Denton County for 25 years with Comprehensive Gastroenterology P.A. He provides colonoscopy, upper endoscopy, ERCP, endoscopic ultrasound and treatment for the complete range of digestive, liver and pancreatic conditions, with a focus on clear explanations and personal care.

Denton Main Office

3304 Colorado Blvd, Suite 202
Denton, TX 76210

Coppell Office

920 S Beltline Rd
Coppell, TX 75019

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